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From founders to executives to researchers, South Carolinians are developing life-changing technologies and products every day.

South Carolina mobilizes the dynamic flow of resources and information among people, industries and institutions for the prosperity of our citizens. Elevating and connecting the state’s people-driven ecosystem is at the forefront to ensuring global competitiveness and driving future economic growth. The innovation team at SC Commerce embraces a risk-taking culture as we identify, prioritize, develop and launch new assets to support South Carolina’s business community in their relentless pursuits of transformational ideas.

No innovator’s story is the same.

We interviewed over 30 innovators across South Carolina to learn what it takes to break the mold. See more of their stories.

South Carolina has the capital, talent, lab space and vibrant entrepreneurial community to help startups flourish and established companies stay at the forefront of their field.

Research & Development

Bring new ideas to market alongside communities and industry with South Carolina’s 60 colleges and universities. Find a sampling of the state's R&D resources below.

Startup Culture and Support

From mountains to coast and everywhere in between, South Carolina buzzes with a thriving entrepreneurial culture full of support.

Funding Sources and Opportunities

Funding is the life-blood of innovation activities and startups. South Carolina has seen a 27.5x increase in capital invested in startups since 2011 (Pitchbook, Dec. 2022).


Developing New
Risk Capital

Grant Support


An ever-present, highly-skilled talent pipeline is critical for business growth and sustainability.

Free Statewide
Coding School

Software Development

Unifying the voice of 
South Carolina's Tech Industry

Challenge Grant

S.C. Commerce’s Relentless Challenge Grant is eligible to South Carolina-based nonprofit organizations, higher education institutions and municipalities that are implementing new programs that break down barriers to innovation.

of note podcast

Of Note is a podcast on
South Carolina innovation

We're opening up the notebooks of some of the most interesting business minds in the South.

Listen now on:

Apple PodCastStitcherspotify